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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPD4
All Species:
19.7
Human Site:
T742
Identified Species:
43.33
UniProt:
Q9NXE4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE4
NP_060221.2
827
93352
T742
S
F
C
R
Y
H
L
T
E
P
G
L
A
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543560
827
93189
T742
S
F
C
R
Y
H
L
T
E
P
G
V
T
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR5
823
93257
T738
S
F
C
R
Y
H
L
T
E
P
A
L
S
N
R
Rat
Rattus norvegicus
NP_001161278
823
93261
T738
S
F
C
R
Y
H
L
T
E
P
A
L
S
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509989
509
58534
T425
S
L
C
R
Y
H
L
T
D
P
F
G
E
E
R
Chicken
Gallus gallus
XP_415236
827
94779
T743
R
F
C
R
Y
H
L
T
N
P
H
L
V
H
K
Frog
Xenopus laevis
Q5XHG1
824
93777
H739
F
L
G
K
L
C
R
H
H
L
T
S
S
S
R
Zebra Danio
Brachydanio rerio
Q6PFJ7
791
89972
R704
D
F
L
G
S
V
G
R
H
Y
L
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650124
767
86929
Y681
G
F
Y
V
R
D
D
Y
F
G
K
V
A
R
Q
Honey Bee
Apis mellifera
XP_623882
744
86631
N660
K
L
P
K
R
T
Q
N
G
L
S
C
G
Y
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784153
874
98584
N772
A
M
A
R
W
Y
F
N
P
R
G
S
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
89.8
90.3
N.A.
46.1
74.9
66.2
60.5
N.A.
24.2
29.5
N.A.
31
Protein Similarity:
100
N.A.
N.A.
94.5
N.A.
93.8
93.9
N.A.
51.8
83.9
77.6
71.9
N.A.
42.2
47.4
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
80
N.A.
80
80
N.A.
60
60
13.3
13.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
66.6
66.6
26.6
20
N.A.
26.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
0
19
0
19
0
0
% A
% Cys:
0
0
55
0
0
10
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
37
0
0
0
10
10
10
% E
% Phe:
10
64
0
0
0
0
10
0
10
0
10
0
0
0
0
% F
% Gly:
10
0
10
10
0
0
10
0
10
10
28
10
10
10
0
% G
% His:
0
0
0
0
0
55
0
10
19
0
10
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
19
0
0
0
0
0
0
10
0
0
0
10
% K
% Leu:
0
28
10
0
10
0
55
0
0
19
10
37
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
10
0
0
0
0
19
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
55
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
64
19
0
10
10
0
10
0
0
0
10
55
% R
% Ser:
46
0
0
0
10
0
0
0
0
0
10
28
37
28
19
% S
% Thr:
0
0
0
0
0
10
0
55
0
0
10
0
10
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
19
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
55
10
0
10
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _